畜禽选择信号检测方法及其统计学问题

doi:10.11843/j.issn.0366-6964.2018.06.001

摘要/Abstract

摘要：

畜禽选择信号的研究随着基因组大数据的爆发式增长，已经成为目前畜禽群体遗传学研究与重要经济性状基因定位的一个重要手段。使用恰当的选择信号方法，了解选择信号检测中的统计学问题，对于准确解析畜禽适应性进化的潜在遗传机制，精细定位重要经济性状的候选基因具有重要的意义。围绕畜禽基因组选择信号研究概况，本文对选择信号的概念、检验统计量类别、畜禽选择信号检测的影响因素及相关统计学问题进行了综述，以期为进一步拓展选择信号的研究思路提供参考。

Abstract:

Identification of selection signatures have become an important tool in population genetics and gene mapping of economically important traits with the explosion of genomic data. Using proper statistical methods and understanding the potential statistical problems in identification of selection signature are of great significance to accurately locate the candidate genes affecting economically important traits and reveal the potential genetic mechanism of adaptive evolution of livestock and poultry. This paper reviews the concept, the category of testing statistics of selection signature, the influencing factors and the related statistical problems in identification of selection signatures. It is expected to provide a reference for further research on identification of selection signatures.

中图分类号:

S813

薛周舣源, 宋显威, 吴林慧, 王露珍, 崔家安, 孙章健, 张政, 马云龙. 畜禽选择信号检测方法及其统计学问题[J]. 畜牧兽医学报, 2018, 49(6): 1099-1107.

XUE Zhou-yi-yuan, SONG Xian-wei, WU Lin-hui, WANG Lu-zhen, CUI Jia-an, SUN Zhang-jian, ZHANG Zheng, MA Yun-long. The Identification Methods of Selection Signatures in Livestock and Its Statistical Problems[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2018, 49(6): 1099-1107.

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